Using a portable version of Adobe software carries significant downsides: Security Risks
: Adobe does not officially release "portable" versions of its Creative Cloud apps. These versions are usually created by third parties and may be found on various software sharing sites. adobe+media+encoder+cc+2019161255+portable
The software is compatible with various file systems, including FAT32, NTFS, and APFS. Using a portable version of Adobe software carries
Dynamic Link (the feature that lets you send files directly from Premiere to Media Encoder without rendering first) rarely works in portable setups because the programs cannot "see" each other without a standard installation. adobe+media+encoder+cc+2019161255+portable
Support for almost any format, including H.264, HEVC, and ProRes.