In Thai culture, the concept of kathoey is often associated with the idea of "phak khun khao" or "being a third gender," which acknowledges the existence of individuals who do not strictly identify as male or female. This cultural context has allowed for a relatively more accepting attitude towards kathoey individuals compared to other parts of the world.
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Generally, individuals in this community prefer female pronouns (she/her). If you aren't sure, it is polite to follow their lead or ask respectfully. In Thai culture, the concept of kathoey is