The MicrosoftSetupUI.framework error primarily affects older Office for Mac versions due to corrupted files or macOS incompatibility, requiring updated Microsoft AutoUpdate (MAU) or manual patch installation. For modern versions, standalone update packages are available, while legacy versions often require reinstallation rather than manual patching. Detailed update history and patching information is available on the Microsoft Learn website . MSO15.11.2Patch - GitHub Gist
Microsoft does not provide "patches" for individual frameworks. Instead, you must download the Microsoft AutoUpdate (MAU) Microsoftsetupui.framework Mac Patch Download
If a specific app like Excel is failing because of this framework, you may need to clear the local cache: The MicrosoftSetupUI