Wilms Tumor Ppt New 2021

| Therapy | Risk | |---------|------| | Doxorubicin | Cardiomyopathy (20% by 30 years) | | Abdominal radiation | Secondary cancers (osteosarcoma, breast), scoliosis | | Nephrectomy | Hypertension, proteinuria, CKD Stage 2–3 | | Vincristine | Neuropathy, constipation, hearing loss |

For a "new" PPT, these specific details from authoritative sources can add depth: wilms tumor ppt new

Recent large-scale sequencing (TARGET initiative) identifies MYCN amplification and SIX1/2 mutations as adverse prognostic factors independent of histology. | Therapy | Risk | |---------|------| | Doxorubicin