While a patched version of Xilinx ISE 10.1 can offer several benefits, there are also implications and considerations to keep in mind:

He launched the ISE Project Navigator. The splash screen flickered—once, twice—then loaded with a strange, glitched icon where the Xilinx logo should have been: a simple 101 in a red square.

Key capabilities:

: Replace the existing libPortability.dll with a version that has SmartHeap disabled. How-to : Go to C:\Xilinx\10.1\ISE\lib\nt64 (or your install path).